Anti-DDX3X Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DDX3X Polyclonal Antibody

品牌:solarbio | 货号:K004098P

英文名称 Anti-DDX3X Polyclonal Antibody
宿主 Rabbit
别名 CAP-Rf;DBX;DDX14;DDX3;HLP2;MRX102
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human Mouse
蛋白分子量 73kDa
Gene ID 1654
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human DDX3X
性状 液体
Public Immunogen Range Recombinant protein of human DDX3X
Subcellular Locations Cytoplasm Mitochondrion outer membrane Nucleus speckle
Swiss Prot O00571
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.