Anti-OSM Polyclonal Antibody
品牌:solarbio | 货号:K004354P
英文名称 |
Anti-OSM Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
OSM |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
28kDa |
Gene ID |
5008 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human OSM |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human OSM |
Subcellular Locations |
Secreted |
Swiss Prot |
P13725 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |