Anti-OSM Polyclonal Antibody
品牌:solarbio | 货号:K004354P
| 英文名称 | Anti-OSM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | OSM |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 28kDa |
| Gene ID | 5008 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human OSM |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human OSM |
| Subcellular Locations | Secreted |
| Swiss Prot | P13725 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |