Anti-FDPS Polyclonal Antibody
品牌：solarbio | 货号：K004178P
| 英文名称 | Anti-FDPS Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FPPS;FPS;POROK9 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 48kDa |
| Gene ID | 2224 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FDPS |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FDPS |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P14324 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene. |