Anti-Ku-70 Polyclonal Antibody
品牌:solarbio | 货号:K106656P
英文名称 |
Anti-Ku-70 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CTC75;CTCBF;G22P1;XRCC6;ML8;TLAA |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:20-50. |
交叉反应 |
Human |
蛋白分子量 |
70kDa |
Gene ID |
2547 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human Ku-70 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human Ku-70 |
Subcellular Locations |
Nucleus |
Swiss Prot |
P12956 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3′-5′ direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. |