Anti-SETMAR Polyclonal Antibody
品牌:solarbio | 货号:K007471P
| 英文名称 | Anti-SETMAR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Mar1;METNASE |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 76kDa |
| Gene ID | 6419 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SETMAR |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SETMAR |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q53H47 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |