Anti-RTKN Polyclonal Antibody
品牌：solarbio | 货号：K004751P
| 英文名称 | Anti-RTKN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RTKN |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 63kDa |
| Gene ID | 6242 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RTKN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RTKN |
| Subcellular Locations | Cytosol |
| Swiss Prot | Q9BST9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. |