Anti-Acvrl1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Acvrl1 Polyclonal Antibody

品牌:solarbio | 货号:K106892P

英文名称 Anti-Acvrl1 Polyclonal Antibody
宿主 Rabbit
别名 ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I;activin A receptor like type 1
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 57kDa
Gene ID 25237
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human Acvrl1
性状 液体
Public Immunogen Range A synthetic peptide of human Acvrl1
Subcellular Locations Cell membrane Extracellular matrix Secreted
Swiss Prot P80203
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.