Anti-Acvrl1 Polyclonal Antibody
品牌:solarbio | 货号:K106892P
英文名称 |
Anti-Acvrl1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I;activin A receptor like type 1 |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
57kDa |
Gene ID |
25237 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human Acvrl1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human Acvrl1 |
Subcellular Locations |
Cell membrane Extracellular matrix Secreted |
Swiss Prot |
P80203 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |