Anti-ITGAL Polyclonal Antibody
品牌:solarbio | 货号:K106784P
英文名称 |
Anti-ITGAL Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD11A;LFA-1A |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
128kDa |
Gene ID |
3683 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ITGAL |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ITGAL |
Subcellular Locations |
Cell membrane |
Swiss Prot |
P20701 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |