Anti-HIST3H3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HIST3H3 Polyclonal Antibody

品牌:solarbio | 货号:K106623P

英文名称 Anti-HIST3H3 Polyclonal Antibody
宿主 Rabbit
别名 Histone H3.3;H3.3 ;H3.3A;H3.3B;H3F3A
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 17kDa
Gene ID 8350
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human HIST3H3
性状 液体
Public Immunogen Range A synthetic peptide of human HIST3H3
Subcellular Locations Nucleus
Swiss Prot P06353
克隆类型 Polyclonal Antibody
背景资料 Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.