Anti-GAD65 Polyclonal Antibody
品牌：solarbio | 货号：K106572P
| 英文名称 | Anti-GAD65 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GAD2;DCE2;MGC161605;MGC161607 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 65kDa |
| Gene ID | 2572 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human GAD65 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human GAD65 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | Q05329 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |