Anti-CREB-1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CREB-1 Polyclonal Antibody

品牌:solarbio | 货号:K106554P

英文名称 Anti-CREB-1 Polyclonal Antibody
宿主 Rabbit
别名 CREB;Active transcription factor CREB;CREB1_HUMAN;MGC9284
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 37kDa
Gene ID 1385
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CREB-1
性状 液体
Public Immunogen Range A synthetic peptide of human CREB-1
Subcellular Locations Nucleus
Swiss Prot P16220
克隆类型 Polyclonal Antibody
背景资料 Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1.