Anti-GFRA2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GFRA2 Polyclonal Antibody

品牌:solarbio | 货号:K007501P

英文名称 Anti-GFRA2 Polyclonal Antibody
宿主 Rabbit
别名 GDNFRB;NRTNR-ALPHA;NTNRA;RETL2;TRNR2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:10-50.
交叉反应 Human Mouse
蛋白分子量 52kDa
Gene ID 2675
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human GFRA2
性状 液体
Public Immunogen Range A synthetic peptide of human GFRA2
Subcellular Locations Cytoplasm
Swiss Prot O00451
克隆类型 Polyclonal Antibody
背景资料 Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.