Anti-IL-23 Polyclonal Antibody
品牌：solarbio | 货号：K106452P
| 英文名称 | Anti-IL-23 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL23A;IL-23p19;IL-23-A;SGRF |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 27kDa |
| Gene ID | 51561 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL-23 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL-23 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9NPF7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |