Anti-CDH3 Polyclonal Antibody
品牌:solarbio | 货号:K008218P
英文名称 |
Anti-CDH3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CDHP;HJMD;PCAD |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:5-20. |
交叉反应 |
Human Mouse |
蛋白分子量 |
91kDa |
Gene ID |
1001 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CDH3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CDH3 |
Subcellular Locations |
Membrane Cytoplasm |
Swiss Prot |
P22223 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. |