Anti-MASP1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MASP1 Polyclonal Antibody

品牌:solarbio | 货号:K008185P

英文名称 Anti-MASP1 Polyclonal Antibody
宿主 Rabbit
别名 3MC1;MAP1;MASP;RaRF;CRARF;MASP3;MAp44;PRSS5;CRARF1
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量 79kDa
Gene ID 5648
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MASP1
性状 液体
Public Immunogen Range Recombinant protein of human MASP1
Swiss Prot P48740
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.