Anti-CA9 Polyclonal Antibody
品牌：solarbio | 货号：K008117P
| 英文名称 | Anti-CA9 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MN;CAIX |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 50kDa |
| Gene ID | 768 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CA9 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CA9 |
| Subcellular Locations | Membrane |
| Swiss Prot | Q16790 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. |