Anti-MECOM Polyclonal Antibody
品牌:solarbio | 货号:K008042P
英文名称 |
Anti-MECOM Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EVI1;MDS1;KMT8E;PRDM3;RUSAT2;MDS1-EVI1;AML1-EVI-1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:30-150. |
交叉反应 |
Human Mouse |
蛋白分子量 |
118kDa |
Gene ID |
2122 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human MECOM |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human MECOM |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q03112 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. |