Anti-NLRP10 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NLRP10 Polyclonal Antibody

品牌:solarbio | 货号:K007780P

英文名称 Anti-NLRP10 Polyclonal Antibody
宿主 Rabbit
别名 NOD8;PAN5;PYNOD;NALP10;CLR11.1
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 75kDa
Gene ID 338322
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human NLRP10
性状 液体
Public Immunogen Range A synthetic peptide of human NLRP10
Swiss Prot Q86W26
克隆类型 Polyclonal Antibody
背景资料 Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.