Anti-NLRP10 Polyclonal Antibody
品牌:solarbio | 货号:K007780P
| 英文名称 | Anti-NLRP10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NOD8;PAN5;PYNOD;NALP10;CLR11.1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 75kDa |
| Gene ID | 338322 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NLRP10 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NLRP10 |
| Swiss Prot | Q86W26 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. |