Anti-NLRP10 Polyclonal Antibody
品牌:solarbio | 货号:K007780P
英文名称 |
Anti-NLRP10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NOD8;PAN5;PYNOD;NALP10;CLR11.1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
75kDa |
Gene ID |
338322 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NLRP10 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NLRP10 |
Swiss Prot |
Q86W26 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. |