Anti-BRK1 Polyclonal Antibody
品牌：solarbio | 货号：K007721P
| 英文名称 | Anti-BRK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MDS027;hHBrk1;C3orf10;HSPC300 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 9kDa |
| Gene ID | 55845 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BRK1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BRK1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q8WUW1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.? |