Anti-BCL6 Polyclonal Antibody
品牌：solarbio | 货号：K005059P
| 英文名称 | Anti-BCL6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BCL5;BCL6A;LAZ3;ZBTB27;ZNF51 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 79kDa |
| Gene ID | 604 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BCL6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BCL6 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P41182 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |