Anti-DNMT3A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DNMT3A Polyclonal Antibody

品牌:solarbio | 货号:K006733P

英文名称 Anti-DNMT3A Polyclonal Antibody
宿主 Rabbit
别名 DNMT3A2;M.HsaIIIA
应用 IHC
稀释比例 IHC 1:100-300.
交叉反应 Human Mouse Rat
蛋白分子量 102kDa
Gene ID 1788
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human DNMT3A
性状 液体
Public Immunogen Range Recombinant protein of human DNMT3A
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q9Y6K1
克隆类型 Polyclonal Antibody
背景资料 CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.