Anti-AK1 Polyclonal Antibody
品牌：solarbio | 货号：K006661P
| 英文名称 | Anti-AK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HTL-S-58j |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 203 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AK1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AK1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P00568 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. |