Anti-CD11B Polyclonal Antibody
品牌:solarbio | 货号:K006620P
英文名称 |
Anti-CD11B Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ITGAM;CD11B;CR3A |
应用 |
WB IHC FC |
稀释比例 |
WB 1:2000. IHC 1:25. FC 1:10-50. |
交叉反应 |
Human |
蛋白分子量 |
180kDa |
Gene ID |
3684 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CD11B |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CD11B |
Subcellular Locations |
Cell membrane Membrane |
Swiss Prot |
P11215 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (‘Mac-1’), or inactivated-C3b (iC3b) receptor 3 (‘CR3’). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. |