Anti-CD11B Polyclonal Antibody
品牌：solarbio | 货号：K006620P
| 英文名称 | Anti-CD11B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ITGAM;CD11B;CR3A |
| 应用 | WB IHC FC |
| 稀释比例 | WB 1:2000. IHC 1:25. FC 1:10-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 180kDa |
| Gene ID | 3684 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CD11B |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CD11B |
| Subcellular Locations | Cell membrane Membrane |
| Swiss Prot | P11215 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (‘Mac-1’), or inactivated-C3b (iC3b) receptor 3 (‘CR3’). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. |