Anti-CD11B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD11B Polyclonal Antibody

品牌:solarbio | 货号:K006620P

英文名称 Anti-CD11B Polyclonal Antibody
宿主 Rabbit
稀释比例 WB 1:2000. IHC 1:25. FC 1:10-50.
交叉反应 Human
蛋白分子量 180kDa
Gene ID 3684
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD11B
性状 液体
Public Immunogen Range A synthetic peptide of human CD11B
Subcellular Locations Cell membrane Membrane
Swiss Prot P11215
克隆类型 Polyclonal Antibody
背景资料 CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (‘Mac-1’), or inactivated-C3b (iC3b) receptor 3 (‘CR3’). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.