Anti-RGS14 Polyclonal Antibody
品牌：solarbio | 货号：K006132P
| 英文名称 | Anti-RGS14 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RGS14 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 61kDa |
| Gene ID | 10636 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RGS14 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RGS14 |
| Subcellular Locations | Cell junction Cell membrane Cell projection Cytoplasm Membrane Nucleus PML body centrosome cytoskeleton dendrite dendritic spine microtubule organizing center postsynaptic cell membrane postsynaptic density spindle spindle pole synapse |
| Swiss Prot | O43566 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |