Anti-COL6A1 Polyclonal Antibody
品牌：solarbio | 货号：K006016P
| 英文名称 | Anti-COL6A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BTHLM1;OPLL;UCHMD1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 109kDa |
| Gene ID | 1291 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COL6A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COL6A1 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | P12109 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. |