Anti-RFC5 Polyclonal Antibody
品牌:solarbio | 货号:K005636P
| 英文名称 | Anti-RFC5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RFC36 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 38kDa |
| Gene ID | 5985 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RFC5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RFC5 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P40937 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants. |