Anti-ATP1A1 Polyclonal Antibody
品牌:solarbio | 货号:K005524P
英文名称 |
Anti-ATP1A1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ATP1A1;MGC3285;MGC51750;Na;K-ATPase; |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Rat |
蛋白分子量 |
113kDa |
Gene ID |
476 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ATP1A1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ATP1A1 |
Subcellular Locations |
Cell membrane Melanosome Multi-pass membrane protein |
Swiss Prot |
P05023 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. |