Anti-NYX Polyclonal Antibody
品牌:solarbio | 货号:K005492P
| 英文名称 | Anti-NYX Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CLRP;CSNB1;CSNB1A;CSNB4;NBM1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 52kDa |
| Gene ID | 60506 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NYX |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NYX |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | Q9GZU5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. |