Anti-GTF2A2 Polyclonal Antibody
品牌:solarbio | 货号:K005388P
英文名称 |
Anti-GTF2A2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HsT18745;T18745;TF2A2;TFIIA;TFIIA-12;TFIIA-gamma;TFIIAS |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
12kDa |
Gene ID |
2958 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GTF2A2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GTF2A2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
P52657 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]). |