Anti-OPRL1 Polyclonal Antibody
品牌:solarbio | 货号:K003595P
英文名称 |
Anti-OPRL1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
KOR-3;NOCIR;NOP;NOPr;OOR;ORL1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
41kDa |
Gene ID |
4987 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human OPRL1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human OPRL1 |
Subcellular Locations |
Cell membrane Cytoplasmic vesicle Multi-pass membrane protein |
Swiss Prot |
P41146 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5′-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. |