Anti-OPRL1 Polyclonal Antibody
品牌：solarbio | 货号：K003595P
| 英文名称 | Anti-OPRL1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KOR-3;NOCIR;NOP;NOPr;OOR;ORL1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 41kDa |
| Gene ID | 4987 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human OPRL1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human OPRL1 |
| Subcellular Locations | Cell membrane Cytoplasmic vesicle Multi-pass membrane protein |
| Swiss Prot | P41146 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5′-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. |