Anti-DYNLL1 Polyclonal Antibody
品牌：solarbio | 货号：K007016P
| 英文名称 | Anti-DYNLL1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LC8;PIN;DLC1;DLC8;LC8a;DNCL1;hdlc1;DNCLC1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 10kDa |
| Gene ID | 8655 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DYNLL1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DYNLL1 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | P63167 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. |