Anti-CHMP2B Polyclonal Antibody
品牌：solarbio | 货号：K003968P
| 英文名称 | Anti-CHMP2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALS17;CHMP2.5;DMT1;VPS2-2;VPS2B |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 24kDa |
| Gene ID | 25978 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CHMP2B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CHMP2B |
| Subcellular Locations | Cytoplasm Late endosome membrane Peripheral membrane protein cytosol |
| Swiss Prot | Q9UQN3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. |