Anti-CHMP2B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CHMP2B Polyclonal Antibody

品牌:solarbio | 货号:K003968P

英文名称 Anti-CHMP2B Polyclonal Antibody
宿主 Rabbit
别名 ALS17;CHMP2.5;DMT1;VPS2-2;VPS2B
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 24kDa
Gene ID 25978
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CHMP2B
性状 液体
Public Immunogen Range Recombinant protein of human CHMP2B
Subcellular Locations Cytoplasm Late endosome membrane Peripheral membrane protein cytosol
Swiss Prot Q9UQN3
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.