Anti-MAPKAPK3 Polyclonal Antibody
品牌：solarbio | 货号：K005331P
| 英文名称 | Anti-MAPKAPK3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 3PK;MAPKAP-K3;MAPKAP3;MAPKAPK-3;MDPT3;MK-3 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 43kDa |
| Gene ID | 7867 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MAPKAPK3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MAPKAPK3 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q16644 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. |