Anti-PRKCQ Polyclonal Antibody
品牌：solarbio | 货号：K004242P
| 英文名称 | Anti-PRKCQ Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PRKCT;nPKC-theta |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 82kDa |
| Gene ID | 5588 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PRKCQ |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PRKCQ |
| Subcellular Locations | Cell membrane Cytoplasm Peripheral membrane protein |
| Swiss Prot | Q04759 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. |