Anti-CD86 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD86 Polyclonal Antibody

品牌:solarbio | 货号:K106555P

英文名称 Anti-CD86 Polyclonal Antibody
宿主 Rabbit
别名 B7-2;B7.2;B70;CD28LG2;LAB72
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 40kDa
Gene ID 942
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD86
性状 液体
Public Immunogen Range A synthetic peptide of human CD86
Subcellular Locations Cell membrane Single-pass type I membrane protein
Swiss Prot P42081
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.