Anti-CD86 Polyclonal Antibody
品牌:solarbio | 货号:K106555P
| 英文名称 | Anti-CD86 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | B7-2;B7.2;B70;CD28LG2;LAB72 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 942 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CD86 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CD86 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | P42081 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |