Anti-CD2AP Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD2AP Polyclonal Antibody

品牌:solarbio | 货号:K005464P

英文名称 Anti-CD2AP Polyclonal Antibody
宿主 Rabbit
别名 CMS
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 71kDa
Gene ID 23607
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD2AP
性状 液体
Public Immunogen Range A synthetic peptide of human CD2AP
Subcellular Locations Cell projection Cytoplasm cytoskeleton ruffle
Swiss Prot Q9Y5K6
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.