Anti-MMP11 Polyclonal Antibody
品牌：solarbio | 货号：K003563P
| 英文名称 | Anti-MMP11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SL-3;ST3;STMY3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 55kDa |
| Gene ID | 4320 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MMP11 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MMP11 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | P24347 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP’s, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. |