Anti-ATAD3A Polyclonal Antibody
品牌：solarbio | 货号：K005717P
| 英文名称 | Anti-ATAD3A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HAYOS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 71kDa |
| Gene ID | 55210 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ATAD3A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ATAD3A |
| Subcellular Locations | Mitochondrion inner membrane Mitochondrion matrix Single-pass membrane protein mitochondrion nucleoid |
| Swiss Prot | Q9NVI7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. |