Anti-CKMT2 Polyclonal Antibody
品牌:solarbio | 货号:K005651P
英文名称 |
Anti-CKMT2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
SMTCK |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:20-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
1160 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CKMT2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CKMT2 |
Subcellular Locations |
Intermembrane side Mitochondrion inner membrane Peripheral membrane protein |
Swiss Prot |
P17540 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. |