Anti-CCNE2 Polyclonal Antibody
品牌：solarbio | 货号：K004955P
| 英文名称 | Anti-CCNE2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CYCE2 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 47kDa |
| Gene ID | 9134 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CCNE2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CCNE2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | O96020 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. |