Anti-H2AFY Polyclonal Antibody
品牌:solarbio | 货号:K004965P
英文名称 |
Anti-H2AFY Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
H2A.y;H2A/y;H2AF12M;MACROH2A1.1;mH2A1;macroH2A1.2 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
40kDa |
Gene ID |
9555 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human H2AFY |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human H2AFY |
Subcellular Locations |
Chromosome Nucleus |
Swiss Prot |
O75367 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. |