Anti-NRGN Polyclonal Antibody
品牌:solarbio | 货号:K005842P
英文名称 |
Anti-NRGN Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
RC3;hng |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
8kDa |
Gene ID |
4900 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NRGN |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NRGN |
Subcellular Locations |
Mitochondrion Nucleus |
Swiss Prot |
Q92686 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. |