Anti-TGFB3 Polyclonal Antibody
品牌：solarbio | 货号：K005854P
| 英文名称 | Anti-TGFB3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARVD;ARVD1;LDS5;RNHF;TGF-beta3 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 47kDa |
| Gene ID | 7043 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TGFB3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TGFB3 |
| Subcellular Locations | Secreted |
| Swiss Prot | P10600 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. |