Anti-CKAP5 Polyclonal Antibody
品牌：solarbio | 货号：K005899P
| 英文名称 | Anti-CKAP5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CHTOG;MSPS;TOG;TOGp;ch-TOG |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 225kDa |
| Gene ID | 9793 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CKAP5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CKAP5 |
| Subcellular Locations | Cytoplasm centrosome cytoskeleton microtubule organizing center spindle pole |
| Swiss Prot | Q14008 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. |