Anti-XPC Polyclonal Antibody
品牌：solarbio | 货号：K005780P
| 英文名称 | Anti-XPC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RAD4;XP3;XPCC;p125 |
| 应用 | WB IHC IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IP 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 106kDa |
| Gene ID | 7508 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human XPC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human XPC |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q01831 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |