Anti-SPTLC1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SPTLC1 Polyclonal Antibody

品牌:solarbio | 货号:K006922P

英文名称 Anti-SPTLC1 Polyclonal Antibody
宿主 Rabbit
别名 HSN1;LBC1;LCB1;SPT1;SPTI;HSAN1
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human
蛋白分子量 53kDa
Gene ID 10558
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SPTLC1
性状 液体
Public Immunogen Range Recombinant protein of human SPTLC1
Subcellular Locations Cytoplasm
Swiss Prot O15269
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5′-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.