Anti-SPTLC1 Polyclonal Antibody
品牌:solarbio | 货号:K006922P
英文名称 |
Anti-SPTLC1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HSN1;LBC1;LCB1;SPT1;SPTI;HSAN1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
53kDa |
Gene ID |
10558 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SPTLC1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SPTLC1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O15269 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5′-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. |