Anti-ASGR1 Polyclonal Antibody
品牌:solarbio | 货号:K006943P
英文名称 |
Anti-ASGR1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HL-1;ASGPR;ASGPR1;CLEC4H1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
33kDa |
Gene ID |
432 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ASGR1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ASGR1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P07306 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |