Anti-CASP14 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CASP14 Polyclonal Antibody

品牌:solarbio | 货号:K006645P

英文名称 Anti-CASP14 Polyclonal Antibody
宿主 Rabbit
别名 caspase 14;apoptosis-related cysteine peptidase
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 28kDa
Gene ID 23581
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CASP14
性状 液体
Public Immunogen Range Recombinant protein of human CASP14
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P31944
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.