Anti-IMPDH2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IMPDH2 Polyclonal Antibody

品牌:solarbio | 货号:K003930P

英文名称 Anti-IMPDH2 Polyclonal Antibody
宿主 Rabbit
别名 IMPD2;IMPDH-II
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human Mouse
蛋白分子量 56kDa
Gene ID 3615
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human IMPDH2
性状 液体
Public Immunogen Range Recombinant protein of human IMPDH2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P12268
克隆类型 Polyclonal Antibody
背景资料 This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.