Anti-IMPDH2 Polyclonal Antibody
品牌:solarbio | 货号:K003930P
英文名称 |
Anti-IMPDH2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
IMPD2;IMPDH-II |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
56kDa |
Gene ID |
3615 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human IMPDH2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human IMPDH2 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
P12268 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |