Anti-LONP1 Polyclonal Antibody
品牌:solarbio | 货号:K003775P
英文名称 |
Anti-LONP1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CODASS;LON;LONP;LonHS;PIM1;PRSS15;hLON |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
106kDa |
Gene ID |
9361 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human LONP1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human LONP1 |
Subcellular Locations |
Mitochondrion matrix |
Swiss Prot |
P36776 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. |